KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K5
All Species:
23.64
Human Site:
S615
Identified Species:
52
UniProt:
Q99683
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99683
NP_005914.1
1374
154537
S615
S
V
R
G
V
S
I
S
K
F
E
E
R
C
C
Chimpanzee
Pan troglodytes
XP_001171211
1375
154924
S616
S
V
R
G
V
S
I
S
K
F
E
E
R
C
C
Rhesus Macaque
Macaca mulatta
XP_001111127
1297
143635
R584
C
G
V
S
A
S
K
R
D
E
R
C
C
F
L
Dog
Lupus familis
XP_533420
1645
181128
S886
S
V
R
G
V
S
I
S
K
F
E
E
R
C
C
Cat
Felis silvestris
Mouse
Mus musculus
O35099
1380
154441
S622
S
V
R
G
V
S
I
S
K
F
E
E
R
C
C
Rat
Rattus norvegicus
XP_001073260
1338
150427
S586
S
V
R
G
V
S
I
S
K
F
E
E
R
C
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511920
1243
141469
G556
N
G
D
R
V
I
L
G
K
G
T
Y
G
I
V
Chicken
Gallus gallus
XP_419725
1260
143069
L557
G
E
C
D
G
D
S
L
E
Y
D
Y
E
Y
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001155222
1364
153160
S604
S
V
R
G
V
S
I
S
K
F
D
E
R
S
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477089
1363
155478
L557
Q
K
F
Y
D
M
I
L
E
M
T
A
D
Q
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202919
1288
145042
S576
V
I
G
G
E
V
D
S
D
L
N
E
I
E
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
44.9
68
N.A.
94.1
92.7
N.A.
84.4
80.4
N.A.
71.7
N.A.
40.6
N.A.
N.A.
44.6
Protein Similarity:
100
99.4
61.3
73.1
N.A.
95.8
94.4
N.A.
87.8
87
N.A.
84.1
N.A.
58.2
N.A.
N.A.
60.7
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
13.3
0
N.A.
86.6
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
26.6
20
N.A.
93.3
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
10
0
10
0
0
0
0
0
0
0
0
10
10
46
55
% C
% Asp:
0
0
10
10
10
10
10
0
19
0
19
0
10
0
10
% D
% Glu:
0
10
0
0
10
0
0
0
19
10
46
64
10
10
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
55
0
0
0
10
0
% F
% Gly:
10
19
10
64
10
0
0
10
0
10
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
10
64
0
0
0
0
0
10
10
0
% I
% Lys:
0
10
0
0
0
0
10
0
64
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
19
0
10
0
0
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
55
10
0
0
0
10
0
0
10
0
55
0
0
% R
% Ser:
55
0
0
10
0
64
10
64
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% T
% Val:
10
55
10
0
64
10
0
0
0
0
0
0
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
10
0
19
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _